By John S. Bradley, John D. Nelson et al. (eds.)
New twenty first Edition! This bestselling and familiar source on pediatric antimicrobial therapy offers speedy entry to trustworthy, up to date techniques for remedy of all infectious illnesses in kids.
Practical, evidence-based ideas from the specialists in antimicrobial therapy
- Developed by means of distinct editorial board
- Designed in case you look after teenagers and are confronted with judgements each day
- New at-a-glance tables of bacterial and fungal pathogen susceptibilities to favourite antimicrobials
- New details on neonatal developmental pharmacology
- Includes remedy of parasitic infections and tropical medicine
- Updated checks concerning the power of the advice and the extent of proof for therapy innovations for significant infections
- Anti-infective drug directory, entire with formulations and dosages
- Antibiotic treatment for overweight children
- Antimicrobial prophylaxis/prevention of symptomatic infection
- Maximal grownup dosages and better dosages of a few antimicrobials frequent in children
Read Online or Download 2015 Nelson's Pediatric Antimicrobial Therapy PDF
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Extra info for 2015 Nelson's Pediatric Antimicrobial Therapy
S aureus MSSA: oxacillin/nafcillin IV (AII) MRSA: vancomycin IV (AIII) Alternative for MSSA: cefazolin (AIII) Alternatives for MRSA: linezolid, clindamycin (if susceptible) (BIII) Addition of rifampin if persistently positive cultures – Group B streptococcus Ampicillin or penicillin G IV (AII) – Haemophilus influenzae Ampicillin IV OR cefotaxime IV, IM if ampicillin-resistant Start with IV therapy and switch to oral therapy when clinically stable. Amox/clav PO OR amoxicillin PO if susceptible (AIII).
For mild disease, oral therapy with amox/clav (CIII). Organisms are normal oral flora for rodents. High rate of associated endocarditis. Alternatives: doxycycline; 2nd- and 3rd-generation cephalosporins (CIII). Staphylococcal scalded skin syndrome6,35 Standard: oxacillin 150 mg/kg/day IV div q6h OR cefazolin 100 mg/kg/day IV div q8h (CII) CA-MRSA: clindamycin 30 mg/kg/day IV div q8h (CIII) OR vancomycin 40 mg/kg/day IV q8h (CIII) Burow or Zephiran compresses for oozing skin and intertriginous areas.
Newer data suggest toxicity of antimicrobials may rifampin) if susceptible (BII) not be worth the small clinical benefit of medical therapy over surgery. Adenitis, tuberculous13,14 (M tuberculosis and M bovis) INH 10–15 mg/kg/day (max 300 mg) PO qd, IV for 6 mo AND rifampin 10–20 mg/kg/day (max 600 mg) PO qd, IV for 6 mo AND PZA 20–40 mg/kg/day PO qd for first 2 mo therapy (BI); if suspected multidrug resistance, add ethambutol 20 mg/kg/day PO qd. May need surgical drainage for staph/strep infection; not usually needed for CSD.