By Stephen C. Cowin
This article summarizes the certainty of bone mechanics with accomplished assurance of the histology, body structure, and the mobilephone and molecular biology of the bone. It covers mechanical concepts, mechanical houses of cortical and cancellous bone, bone variation, and clincally comparable concerns. content material: part I. uncomplicated biology -- built-in bone tissue body structure : anatomy and body structure / Webster S. S. Lee -- telephone biology of bone / Robert J. Majeska -- Molecular biology innovations to degree skeletal gene expression / Marian F. younger and Suzanne C. Dieudonne -- growing transgenic mice to check skeletal functionality / Marian F. younger and Tianshun Xu -- Bone mineralization / Adele L. Boskey -- part II. suggestions from mechanics and imaging -- Mechanics of fabrics / Stephen C. Cowin -- Experimental thoughts for bone mechanics / Charles H. Turner and David B. Burr -- In vivo size of bone deformations utilizing pressure gauges / Susannah P. Fritton and Clinton T. Rubin -- Imaging of bone constitution / Peter Ruegsegger -- part III. Mechanical and architectural homes -- Mechanical homes of cortical bone and cancellous bone tissue / X. Edward Guo -- Viscoelastic homes of cortical bone / Roderic Lakes -- Composite types of bone houses / Eliana Lucchinetti -- Dense bone tissue as a molecular composite / Eliana Lucchinetti -- Quantification of cancellous bone structure / Anders Odgaard -- Elastic constants of cancellous bone / Bert van Rietbergen and Rik Huiskes -- power of trabecular bone / Tony M. Keaveny -- Observations of wear and tear in bone / Karl J. Jepsen, Dwight T. Davy, and Ozan Akkus -- Bone harm mechanics / Dwight T. Davy and Karl J. Jepsen -- Ontogenetic adjustments in compact bone fabric houses / John D. Currey -- Mechanical results of postmortem adjustments, maintenance, and allograft bone remedies / R. Bruce Martin and Neil A. Sharkey -- part IV. circulate of fluids in bone -- Blood circulation in bone / Howart Winet -- Interstitial fluid movement / Melissa L. Knothe Tate -- Bone poroelasticity / Stephen C. Cowin -- Streaming potentials in bone / Solomon R. Pollack -- The intrinsic permeability of cancellous bone / Yves P. Arramon and Eric A. Nauman -- part V. Bone model -- Pathophysiology of sensible version of bone in home improvement and service in vivo / Allen E. Goodship and James L. Cunningham -- units and strategies for in vitro mechanical stimulation of bone cells / Thomas D. Brown -- Experiments on phone mechanosensitivity : bone cells as mechanical engineers / Elisabeth H. Burger -- Mechanosensory mechanisms in bone / Stephen C. Cowin and Melvin L. Moss -- The fake premise in Wolff's legislation / Stephen C. Cowin -- Bone modeling and transforming : theories and computation / Richard T. Hart -- Mechanics of bone regeneration / Patrick J. Prendergast and Marjolein C. H. van der Meulen -- part VI. Clinically similar concerns -- functions of bone mechanics / Marta L. Villaraga and Catherine M. Ford -- Noninvasive size of bone integrity / Jonathan J. Kaufman and Robert S. Siffert -- Bone prostheses and implants / Patrick J. Prendergast -- layout and manufacture of bone substitute scaffolds / Scott J. Hollister ... [et al.]. summary: this article summarizes the knowledge of bone mechanics with complete insurance of the histology, body structure, and the phone and molecular biology of the bone. It covers mechanical recommendations, mechanical houses of cortical and cancellous bone, bone version, and clincally comparable matters. learn more...
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Controls. cortices, and large marrow cavities. When strains exceed the remodeling threshold range, as in normal and hypermechanical usage, remodeling is dampened back toward normal levels (see Fig. 13). 11 A Unifying Theory of Bone Remodeling The current concept assumes that signals generated by osteocytes to mechanical loading stimulates bonelining cells to activate remodeling. This concept could not resolve the inconsistencies that remodeling increases both when mechanical loading is exceedingly low and when it is exceedingly high.
A hyaline cartilage model is laid down and grows by apposition from the perichondrium and by proliferation of the cells at the ends; 2. A subperiosteal ring of bone is laid down by intramembranous ossification; 3. The central portion of cartilage anlage calcifies and vascular mesenchyme enters to form the primary endochondral ossification center; 4. fm Page 34 Wednesday, January 31, 2001 6:30 AM 1-34 Bone Mechanics 5. Blood vessels and mesenchyme enter the superior and inferior epiphyseal ossification centers to form articular cartilage and growth plate; 6.
Bone Miner. , 15, 2, 2000. ) neutralized by binding to OPG/OCIF. Thus, the osteoclast pool may be regulated by the ratio of OPGL/ODF to OPG/OCIF in the bone marrow microenvironment. (Why the marrow environment? 4 Function The osteoclasts solubilize both the mineral and organic component of the matrix. Osteoclasts can be either active or inactive and, when active, they are polarized and exhibit ruffled borders. The signals for the selection of sites to be resorbed is unknown. 29,34,35 The mechanism of attachment of osteoclasts to the bone surface is not known (see Fig.